Melanotan II
Research OnlyAlpha-Melanocyte Stimulating Hormone
Melanotan II is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone that binds to melanocortin receptors, particularly MC1R and MC4R. Activation of MC1R on melanocytes stimulates melanin production and distribution, resulting in increased skin pigmentation even without UV exposure.
Dosing Schedule
| Week | Dose | Units (U-100) |
|---|---|---|
| Assessment | 250 mcg | 7.5 units |
| Loading | 250-500 mcg | 7.5-15 units |
| Maintenance | 500 mcg | 15 units |
Frequency: Inject daily until desired tan is achieved (Loading Phase), then inject once weekly to maintain color (Maintenance Phase).

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Visual representation of the dosage ramp-up over the cycle duration.
Reconstitution
3ml
3.33 mg/mL
10 mg
Add 3.0 mL bacteriostatic water to a 10mg vial for a concentration of 3.33 mg/mL.
Administration
Timing Strategy
Administer before bed to minimize potential side effects like nausea or flushing.
Cycle Length
Loading phase until desired tan is achieved, followed by maintenance dosing.
Research Benefits
Stimulates melanogenesis via MC1R activation, leading to increased skin pigmentation. Also exhibits aphrodisiac properties through central nervous system MC4R activation.
Storage Guidelines
Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions.
Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); stable for 2–4 weeks. Avoid freeze–thaw cycles.
Research Purposes Only
This information is for educational and research purposes only. These compounds are not approved for human consumption. Always consult with a qualified professional and adhere to local regulations regarding research chemicals.
Concentration
3.33 mg/mL
(3333 mcg/mL)
Injection Volume
0.07 mL
Draw to this mark on U-100 Syringe
Visual representation on a standard U-100 Insulin Syringe